Home Services Haemoglobin Guidelines R & D Social Issues Support Group Example 1 If both parents have normal haemoglobin, their children will all inherit normal haemoglobin Parent 1 A A Parent 2 A AA AA A AA AA Example 2 If one parent has sickle cell trait and the other parent has normal haemoglobin Parent 1 A A Parent 2 A AA AA S AS AS Example 3 If both parents have sickle cell trait Parent 1 A S Parent 2 A AA AS S AS SS Example 4 If one parent has sickle cell trait and the other has Haemoglobin C trait Parent 1 A S Parent 2 A AA AS C AC SC Example 5 If one parent has sickle cell trait and the other has beta thalassaemia trait Parent 1 A S Parent 2 A AA AS bThal AbThal SbThal Example 6 If one parent has sickle cell trait and the other has sickle cell disease Parent 1 A S Parent 2 S AS SS S AS SS Example 7 If one parent has normal haemoglobin and the other has beta thalassaemia trait Parent 1 A A Parent 2 A AA AA bThal AbThal AbThal Example 8 If one parent has beta thalassaemia trait and the other has beta thalassaemia major (disease) Parent 1 bThal bThal Parent 2 A AbThal AbThal bThal bThalbThal bThalbThal Example 9 If both parents have sickle cell anaemia Parent 1 S S Parent 2 S SS SS S SS SS Example 10 If one parent has normal haemoglobin and the other has sickle cell anaemia Parent 1 A A Parent 2 S AS AS S AS AS Example 11 If both parents have haemoglobin C trait Parent 1 A C Parent 2 A AA AC C AC CC Example 12 If both parents have alpha zero thalassaemia Parent 1 aa -- Parent 2 aa aa / aa aa / -- -- aa / -- -- / --

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